CD56 抗体 (Biotin)
Quick Overview for CD56 抗体 (Biotin) (ABIN118741)
抗原
See all CD56 (NCAM1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes the (Mr 180, 145, 125 kDa) isoforms of the human neural cell adhesion molecule (NCAM) (1).
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免疫原
- Human retinoblastoma tumor tissue, membrane fraction
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亚型
- IgG1
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anti-Neural Cell Adhesion Molecule 1 (NCAM1) (AA 759-858) antibody
NCAM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) antibodyNCAM1 适用: 人, 小鼠, 猴 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 5B1G11 unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) (Internal Region) antibodyVerified NCAM1 适用: 人 FACS, WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) antibodyNCAM1 适用: 人, 大鼠 FACS, WB, IHC, IF, StM 宿主: 小鼠 Monoclonal NCAM1-795 unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) antibody (PerCP)NCAM1 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-188 PerCP
anti-Neural Cell Adhesion Molecule 1 (NCAM1) (AA 568-708) antibodyNCAM1 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 1F6F10 unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) (AA 701-800) antibodyNCAM1 适用: 人, 大鼠, 小鸡 FACS, WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) (AA 340-608) antibodyNCAM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) antibodyNCAM1 适用: 人, 小鼠 FACS, IHC, ICC 宿主: 小鼠 Monoclonal RNL-1 unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) (AA 829-863), (C-Term) antibodyNCAM1 适用: 人 FACS, WB 宿主: 兔 Polyclonal RB51136 unconjugated
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应用备注
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Studies of neural cell adhesion molecule. May also be used to study isoforms of NCAM expressed on different tumor types. Western blot for analysis of isoforms expressed, did not react with any of the leukemias or lymphomas tested (1). Flow cytometric applications (1 μg to stain 6 x 10e5 cells). Not for use in IHC with formalin-fixed, paraffin embedded sections. The binding of ERIC-1 to both normal and neoplastic tissue is lost when tissues are conventionally fixed in formalin and embedded in paraffin. The epitope was preserved when exposed to dehydrating fixatives such as cold acetone (-20 °C) for 5 minutes.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 100 µg/mL (OD280nm)
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缓冲液
- 0.01 M PBS, pH 7.2, containing 2.0 mM EDTA, 1 % BSA as stabilizer and 0.09 % Sodium azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
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别名
- CD56
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背景
- NCAM, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig) like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins. NCAM is expressed on most neuroectodermal derived cell lines, tissues and neoplasm such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma.Synonyms: N-CAM-1, NCAM, NCAM-1, Neural cell adhesion molecule 1
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基因ID
- 4684
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NCBI登录号
- NP_000606
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UniProt
- P13591
抗原
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